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The frequency of adverse reactions have been reported to be between 0.2% and 21%, and they most commonly occur during the initial loading dose of acetylcysteine

To test this data interpretation, we analyzed the GSSG-dependent oxidation of reduced fusion constructs between roGFP2 WT and wild-type PfGrx (PfGrx WT ), the dithiol mutant PfGrx C88S , or the monothiol mutant PfGrx C32S/C88S (Fig

The resulting proteins, PGC-12 and PGC-13 (379 and 370 amino acids long, respectively), contain part of the activation domain and repression domain and completely lack all the C-terminal motifs of PGC-1

doi: 10.3389/fimmu.2020.01238 Received 09 March 2020 Accepted 18 May 2020 Published 01 July 2020 Volume 11 - 2020 Edited by Thomas Griffith, University of Minnesota Twin Cities, United States Reviewed by Lucinia Gainski Danielski, Universidade de Sul de Santa Catarina, Brazil